Previously undetected mutations in bone marrow stem cells of young donors can be passed to recipients

Physicians use bone marrow stem cells from a donor, transplanted into a recipient, to treat patients with certain cancers or blood disorders. The donors for these procedures, whose blood or bone marrow is used for the procedures, are typically young, to optimize the quality of the donor stem cells. Previous studies have found that error-corrected […]

Hyping a New Drug that Treats Pancreatic Cancer

Headlines today are reading, “A study found a drug used to treat ovarian cancer doubled the lifespans of pancreatic cancer patients” (Guzman, 2020). Sounds great, right? A new drug study reports that a new drug called Lynparza from AstraZeneca, based in the UK, “nearly doubled the time patients lived without disease progression” (AstraZeneca website). Let’s […]

We Don’t Treat Disease With Our Drugs, We Treat Surrogates in the Quagmire of the Deregulated, Privatized Drug Approval Process.

Beginning in the 1980s during the Reagan administration, the approval and regulation processes for therapeutics have been deregulated and evolved into an increasingly complex and poorly working system with rampant fraud. Irrespective of the many other failures of the system, the use of surrogate measures has been encouraged and found to be of questionable value […]

The Over-Medicalization of America Continues – Executive “Health” Programs for Profit, but Not Health

The premise of using Executive Health Programs with their associated cardiovascular diagnostic tests is that the results may help reduce mortality from cardiovascular disease through earlier disease detection, more precise risk assessment, and therefore better treatment. As is often the case in medicine, physicians have beliefs about what works despite the evidence against their cherished, […]